Juleen R Zierath Selected Research

AICA ribonucleotide (ZMP)

1/2018	FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle.
1/2017	Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK.
6/2015	Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner.
7/2004	Sending the signal: molecular mechanisms regulating glucose uptake.
5/2003	5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Juleen R Zierath Research Topics

Disease

58	Insulin Resistance 01/2022 - 06/2002
46	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2002
30	Obesity 01/2022 - 08/2002
8	Body Weight (Weight, Body) 01/2021 - 09/2005
7	Inflammation (Inflammations) 01/2022 - 08/2008
7	Metabolic Diseases (Metabolic Disease) 01/2022 - 05/2013
7	Glucose Intolerance 01/2019 - 11/2003
6	Hypoxia (Hypoxemia) 01/2019 - 09/2002
4	Weight Loss (Weight Reduction) 01/2020 - 09/2005
3	Hyperglycemia 01/2022 - 12/2003
3	Overweight 01/2020 - 02/2013
2	Neoplasms (Cancer) 01/2018 - 08/2010
2	Hypertrophy 03/2016 - 06/2006
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2009 - 01/2006
2	Diabetes Mellitus 11/2003 - 06/2002
1	Non-alcoholic Fatty Liver Disease 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2020
1	Starvation 01/2018
1	Genetic Predisposition to Disease (Genetic Predisposition) 11/2016
1	Weight Gain 03/2016
1	Spinal Cord Injuries (Spinal Cord Injury) 11/2015

Drug/Important Bio-Agent (IBA)

60	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 06/2002
49	Insulin (Novolin)FDA Link 01/2022 - 06/2002
16	LipidsIBA 01/2020 - 03/2007
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
7	Messenger RNA (mRNA)IBA 01/2020 - 09/2005
7	Protein Isoforms (Isoforms)IBA 01/2019 - 09/2002
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2010 - 09/2005
6	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 01/2006
6	CytokinesIBA 01/2018 - 06/2007
5	Triglycerides (Triacylglycerol)IBA 01/2019 - 09/2004
5	AICA ribonucleotide (ZMP)IBA 01/2018 - 05/2003
4	Diacylglycerol KinaseIBA 01/2022 - 02/2008
4	Amino Acids FDA Link 01/2022 - 01/2013
4	Nonesterified Fatty Acids (NEFA)IBA 01/2020 - 01/2006
4	Interleukin-6 (Interleukin 6)IBA 01/2018 - 09/2005
4	Phosphotransferases (Kinase)IBA 08/2008 - 12/2003
4	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 05/2005 - 09/2002
3	ProteomeIBA 01/2022 - 11/2014
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 08/2010
3	LeptinIBA 01/2022 - 08/2002
3	PalmitatesIBA 01/2020 - 02/2013
3	MicroRNAs (MicroRNA)IBA 12/2019 - 09/2013
3	CarbohydratesIBA 01/2019 - 10/2015
3	Serine (L-Serine)FDA Link 01/2017 - 09/2005
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2019
2	Peptides (Polypeptides)IBA 10/2021 - 01/2019
2	Pharmaceutical PreparationsIBA 10/2021 - 08/2010
2	Branched-Chain Amino AcidsIBA 01/2021 - 11/2016
2	Insulin ReceptorIBA 12/2019 - 03/2006
2	RNA (Ribonucleic Acid)IBA 12/2019 - 02/2013
2	CeramidesIBA 01/2018 - 03/2007
2	EnzymesIBA 01/2018 - 02/2012
2	DiglyceridesIBA 01/2017 - 02/2008
2	AMP-Activated Protein KinasesIBA 10/2015 - 09/2002
2	Proteasome InhibitorsIBA 11/2014 - 08/2010
2	Bortezomib (Velcade)FDA Link 11/2014 - 08/2010
2	GlycogenIBA 04/2010 - 09/2008
2	CalcineurinIBA 09/2008 - 09/2005
2	Small Interfering RNA (siRNA)IBA 08/2008 - 03/2007
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2006 - 03/2003
1	Lipoproteins (Lipoprotein)IBA 01/2022
1	Phosphocreatine (Neoton)IBA 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	ChromatinIBA 10/2021
1	Transcription Factors (Transcription Factor)IBA 10/2021
1	UbiquinoneIBA 01/2021
1	Insulin Receptor Substrate ProteinsIBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Keto AcidsIBA 01/2021
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2021
1	LDL CholesterolIBA 01/2019
1	Blood Glucose (Blood Sugar)IBA 01/2019
1	Vitamin D FDA LinkGeneric 01/2019
1	CLOCK ProteinsIBA 01/2019
1	Exosome Multienzyme Ribonuclease ComplexIBA 01/2019
1	Phosphatidylcholines (Phosphatidylcholine)IBA 01/2019
1	hydroxide ionIBA 01/2019
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2018
1	SphingolipidsIBA 01/2018
1	palmitoleic acidIBA 01/2018
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2018
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018
1	HydrolasesIBA 01/2017
1	Carboxylesterase (Hydrolase S)IBA 01/2017
1	Glycogen Synthase (Synthase I)IBA 01/2017
1	Multifunctional EnzymesIBA 01/2017
1	Leucine (L-Leucine)FDA Link 11/2016
1	Valine (L-Valine)FDA Link 11/2016
1	Isoleucine (L-Isoleucine)FDA Link 11/2016
1	KynurenineIBA 10/2016
1	Tryptophan (L-Tryptophan)FDA Link 10/2016
1	salicylhydroxamic acid (SHAM)IBA 03/2016
1	MyostatinIBA 11/2015

Therapy/Procedure

3	Therapeutics 10/2021 - 07/2004
1	Glycemic Control 01/2021
1	Endurance Training 01/2017
1	Bariatric Surgery 02/2016